产品货号：
Z19742
中文名称：
LKB1/STK11抗体
英文名称：
Anti-LKB1/STK11 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-LKB1/STK11 Antibody |
| 指标别名 | LKB1;PJS;serine/threonine kinase 11;STK11;STK11/LKB1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB |
| 基因名称 | STK11 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | LKB1 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human LKB1.The immunogen is located within amino acids 310 - 360 of LKB1. |
| 计算分子量 | 49kDa |
| 成分 | LKB1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | LKB1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The LKB1 serine/threonine protein kinase was initially identified as a tumor suppressor gene mutated in human Peutz-Jeghers syndrome (PJS),a condition resulting in the growth of numerous intestinal polyps classed as hamartomas.LKB1 exists as a heterotrimeric complex with two other proteins,Ste20-related adaptor protein (STRAD) and MO25.Together,this complex can phsophorylate and activate the AMP-activate protein kinase (AMPK).Following AMPK activation by LKB1,AMPK then phosphorylates TSC1 and TSC2,key components of the metabolism-regulating TOR signaling pathway,which antagonizes the activation for the TOR pathway.LKB1 has also been shown to play a fundamental role in controlling the spatial orientation of structures required to maintain an ordered,polarized epithelium. |
| Uniprot ID | Q15831 |
| 基因名全称 | Serine/threonine kinase 11 |
| 蛋白名全称 | Serine/threonine kinase 11 |
| 推荐稀释比 | LKB1 antibody can be used for detection of LKB1 by Western blot at 1μg/mL.LKB1 often migrates at a higher than expected molecular weight in SDS-PAGE.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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